Quickly get hold of sections as thin or thick as your application necessitates, without stressing about shedding or distorting worthwhile tissue samples.
Megatome is usually a vibrating microtome designed to section a broad array of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With significant blade vibrating frequency and minimized blade deflection, Megatome permits high-throughput tissue sectioning with uniform surface profile, along with nominal tissue hurt and knowledge decline.
Antibodies may well acquire weeks to diffuse via only a few millimeters of tissue, using a steep labeling gradient from surface area to core.
Megatome is made for accuracy: the blade vibrates at the next frequency and larger amplitude variety than other microtomes, and includes a unique deflection control mechanism.
SE makes use of a rotational electrical area to disperse hugely electromobile molecules (for example antibodies or surfactant micelles) during a porous sample without having detrimental electrically billed structures inside the tissue. This allows 2-4 working day clearing of intact organs,
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Megatome is really a novel microtome that permits for prime-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with nominal tissue damage and knowledge loss.
eFLASH is usually a quick tissue labeling technique which allows for uniform entire-organ staining in twenty rounds of labeling.
The SmartSPIM mild sheet microscope provides unparalleled resolution and acquisition pace throughout intact tissue volumes, even though its modular style means that you can improve and customise person parts.
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Leverage the Clear+ tissue clearing approach, as well as eFLASH and patented stochastic electrotransport systems, to rapidly distinct and label complete organs. Essential highlights and options include:
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